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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
30.61
Human Site:
S157
Identified Species:
48.1
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
S157
L
Q
K
A
G
K
L
S
P
L
K
V
Q
P
K
Chimpanzee
Pan troglodytes
XP_523125
963
104993
S157
L
Q
K
A
G
K
L
S
P
L
K
V
Q
P
K
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
S158
L
Q
K
A
G
K
L
S
P
L
K
V
Q
P
K
Dog
Lupus familis
XP_532364
964
105327
S158
L
Q
K
A
G
K
L
S
P
L
R
V
Q
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
S158
L
Q
K
A
G
K
L
S
P
L
K
V
Q
S
K
Rat
Rattus norvegicus
Q62751
963
104783
S158
L
Q
K
A
G
K
L
S
P
L
K
V
Q
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
S205
A
K
T
A
A
R
L
S
P
L
K
V
Q
L
R
Chicken
Gallus gallus
Q5ZLQ4
965
105344
S159
Q
K
P
T
A
K
L
S
P
L
K
G
Q
P
R
Frog
Xenopus laevis
Q6NTP2
955
104418
P151
P
A
V
E
T
H
R
P
T
T
T
P
G
K
T
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
V131
R
C
P
T
D
L
I
V
D
H
S
L
Q
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
S131
A
D
L
V
I
D
H
S
V
Q
V
D
F
A
R
Honey Bee
Apis mellifera
XP_392993
890
98796
Q131
L
V
I
D
H
S
I
Q
V
D
F
F
R
T
K
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
G132
S
V
Q
V
D
H
Y
G
N
L
E
A
L
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
D135
I
D
H
S
V
Q
V
D
V
A
R
S
E
N
A
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
S26
V
S
N
L
T
R
D
S
K
V
N
Q
N
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
53.3
53.3
0
6.6
N.A.
6.6
13.3
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
73.3
66.6
0
20
N.A.
13.3
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
47
14
0
0
0
0
7
0
7
0
14
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
7
14
7
7
7
7
7
0
7
0
0
7
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
7
7
0
0
% F
% Gly:
0
0
0
0
40
0
0
7
0
0
0
7
7
0
0
% G
% His:
0
0
7
0
7
14
7
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
7
0
7
0
14
0
0
0
0
0
0
7
0
% I
% Lys:
0
14
40
0
0
47
0
0
7
0
47
0
0
7
54
% K
% Leu:
47
0
7
7
0
7
54
0
0
60
0
7
7
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
7
0
7
7
0
% N
% Pro:
7
0
14
0
0
0
0
7
54
0
0
7
0
40
0
% P
% Gln:
7
40
7
0
0
7
0
7
0
7
0
7
60
0
0
% Q
% Arg:
7
0
0
0
0
14
7
0
0
0
14
0
7
0
20
% R
% Ser:
7
7
0
7
0
7
0
67
0
0
7
7
0
7
0
% S
% Thr:
0
0
7
14
14
0
0
0
7
7
7
0
0
7
7
% T
% Val:
7
14
7
14
7
0
7
7
20
7
7
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _